Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30711495 | 0.89 | KDM4E (0.47) | KDM4ELMNAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7503285 | 0.89 | SMN1; SMN2 (0.62) | CHRM4PRMT5S1PR1SMN1; SMN2NPC1 | |
| SCHEMBL14922380 | 0.88 | SMN1; SMN2 (0.56) | CHRM4PRMT5S1PR1KDM4ELMNA | |
| SCHEMBL8922008 | 0.87 | CHRM4 (0.59) | CHRM4PRMT5LMNAMAPTALDH1A1 | |
| SCHEMBL16897790 | 0.85 | LMNA (0.48) | CHRM4PRMT5KDM4ELMNAMAPT | |
| SCHEMBL14922734 | 0.83 | SMN1; SMN2 (0.55) | CHRM4PRMT5S1PR1KDM4ESMN1; SMN2 | |
| SCHEMBL31127679 | 0.82 | PRMT5 (0.46) | CHRM4PRMT5S1PR1KDM4EALDH1A1 | |
| SCHEMBL27037680 | 0.82 | MRGPRX4 (0.57) | PRMT5S1PR1KDM4ELMNAMAPT | |
| SCHEMBL22193619 | 0.82 | PRMT5 (0.61) | PRMT5KDM4ESMN1; SMN2MRGPRX4GAA | |
| SCHEMBL17477287 | 0.82 | SMN1; SMN2 (0.57) | CHRM4S1PR1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025906-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | SUNDANCE BIOSCIENCES, INC. | 2024-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240025906-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | TYK2, JAK1, JAK3 | CHRM4 4655/4885PRMT5 587/4885S1PR1 2255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.