Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.56 |
| ▸ | RHEB | Q15382 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.45 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29174301 | 1.00 | KMO (0.56) | KMORHEBKMT2AMCL1OXER1 | |
| SCHEMBL5143014 | 0.95 | KMO (0.55) | KMOKMT2AMCL1OXER1TDP1 | |
| SCHEMBL29958540 | 0.95 | KMO (0.55) | KMOKMT2AMCL1OXER1TDP1 | |
| SCHEMBL29957878 | 0.87 | KMO (0.72) | KMORHEBKMT2AMCL1OXER1 | |
| SCHEMBL1576364 | 0.87 | KMO (0.72) | KMORHEBKMT2AMCL1OXER1 | |
| SCHEMBL20037218 | 0.84 | TDP1 (0.53) | KMT2ATDP1MEN1HPGDLMNA | |
| SCHEMBL29174329 | 0.80 | KMO (0.63) | KMORHEBKMT2AMCL1OXER1 | |
| SCHEMBL3871316 | 0.80 | MCL1 (0.47) | MCL1HPGDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL29174300 | 0.79 | KMO (0.44) | KMORHEBMCL1OXER1TDP1 | |
| SCHEMBL2873285 | 0.79 | MCL1 (0.43) | MCL1HPGDLMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396474-A | Plasma kallikrein inhibitors | 武田药品工业株式会社 | 2024-01-12 | — | — | CN | disclosed |