Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20853391 | 1.00 | TERT (0.43) | TERTCCNA2CDK2FERMT2TSHR | |
| SCHEMBL20838501 | 0.93 | TERT (0.41) | TERTFERMT2RAD52KMT2AMAPT | |
| SCHEMBL20838473 | 0.82 | SIGMAR1 (0.45) | TERTFERMT2RAD52KMT2AMAPT | |
| SCHEMBL30711805 | 0.76 | TERT (0.41) | TERTRAD52 | |
| SCHEMBL20853404 | 0.76 | TERT (0.41) | TERTRAD52 | |
| SCHEMBL20853238 | 0.75 | TERT (0.40) | TERTFERMT2RAD52 | |
| SCHEMBL16106479 | 0.70 | PDE5A (0.42) | LMNAGAAPOLBSLC2A1RAB9A | |
| SCHEMBL20853405 | 0.69 | TERT (0.45) | TERT | |
| SCHEMBL30711798 | 0.69 | TERT (0.45) | TERT | |
| SCHEMBL4738026 | 0.67 | MAPT (0.66) | TSHRLMNAGAARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466931-B1 | TETRADENTATE CHELATING MONOQUINOLINE DERIVATIVE, MANUFACTURING METHOD THEREOF, AND APPLICATION OF SAME AS METAL ION REGULATOR FOR NEURODEGENERATIVE DISEASE | UNIV GUANGDONG TECHNOLOGY (CN) | 2024-01-10 | — | — | EP | disclosed |