SCHEMBL30711925

SCHEMBL30711925

N#Cc1ccc(-c2ccnc(Cl)c2)cc1F

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 18/20 0.57
CYP11B1 P15538 16/20 0.57
EGLN2 Q96KS0 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14072361 0.81 CYP11B1 (0.57) CYP11B2CYP11B1EGLN2
SCHEMBL18297999 0.80 CYP11B2 (0.67) CYP11B2CYP11B1
SCHEMBL19933109 0.80 CYP11B2 (0.66) CYP11B2CYP11B1
SCHEMBL31492650 0.80 CYP11B2 (0.66) CYP11B2CYP11B1
SCHEMBL3995795 0.79 CYP11B2 (0.44) CYP11B2CYP11B1
SCHEMBL9612021 0.78 CYP11B2 (0.68) CYP11B2CYP11B1
SCHEMBL12885512 0.78 KMO (0.49) EGLN2
SCHEMBL34472232 0.78 CYP11B2 (0.66) CYP11B2CYP11B1
SCHEMBL3753115 0.77 CYP11B2 (0.58) CYP11B2CYP11B1EGLN2
SCHEMBL29998142 0.77 CYP11B2 (0.58) CYP11B2CYP11B1EGLN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023222115-A1 HYDROXYAMIDE DERIVATIVE AND USE THEREOF 四川汇宇制药股份有限公司 2023-11-23 WO disclosed