SCHEMBL30712019 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	ALOX5AP	P20292	2/20	0.41

▸	FEN1	P39748	2/20	0.41

▸	F2RL1	P55085	1/20	0.35

▸	CYP4F2	P78329	1/20	0.33

▸	CYP4A11	Q02928	1/20	0.33

▸	SSTR5	P35346	1/20	0.32

▸	HRH1	P35367	1/20	0.32

▸	DGAT1	O75907	1/20	0.32

▸	ALDH1A1	P00352	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14658995	0.75	ALOX5AP (0.38)	ALOX5APFEN1F2RL1DGAT1
SCHEMBL19602414	0.75	CSNK2A1 (0.44)	CYP4F2CYP4A11ALDH1A1
SCHEMBL26648940	0.75	ALOX5AP (0.41)	ALOX5APFEN1DGAT1
SCHEMBL5514200	0.75	ALOX5AP (0.46)	ALOX5APFEN1DGAT1ALDH1A1
SCHEMBL8377141	0.74	HTT (0.49)	CYP4F2CYP4A11ALDH1A1
SCHEMBL23580858	0.74	NPC1 (0.41)	ALOX5APFEN1CYP4F2CYP4A11
SCHEMBL4701131	0.74	ALOX5AP (0.42)	ALOX5APFEN1DGAT1
SCHEMBL30811273	0.74	ALDH1A1 (0.47)	ALDH1A1
SCHEMBL25417461	0.74	ALDH1A1 (0.47)	ALDH1A1
SCHEMBL25417856	0.71	ATR (0.37)	ALOX5APFEN1F2RL1DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024008088-A1	COMPOUNDS AS TRK INHIBITORS AND/OR RET INHIBITORS AND USE THEREOF	河南迈英诺医药科技有限公司	2024-01-11	—	—	WO	disclosed