SCHEMBL30712752

SCHEMBL30712752

N#Cc1ccc(-c2cccnc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 5/20 1.00
CYP11B1 P15538 4/20 0.70
CYP17A1 P05093 1/20 0.70
NPY5R Q15761 1/20 0.62
CYP2A6 P11509 3/20 0.60
CYP3A4 P08684 2/20 0.60
ALDH1A1 P00352 1/20 0.60
CYP1A2 P05177 1/20 0.60
CYP19A1 P11511 4/20 0.56
CHRNB2 P17787 1/20 0.55
CHRNA5 P30532 1/20 0.55
CHRNA4 P43681 1/20 0.55
MKNK1 Q9BUB5 2/20 0.52
MKNK2 Q9HBH9 2/20 0.52
KIF11 P52732 1/20 0.52
LMNA P02545 1/20 0.50
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6188982 1.00 CYP11B2 (1.00) CYP11B2CYP11B1CYP17A1NPY5RCYP2A6
SCHEMBL15158494 0.90 CYP11B2 (0.81) CYP11B2CYP11B1CYP17A1NPY5RCYP2A6
Benzonitrile SCHEMBL29165371 0.88 CYP11B2 (0.79) CYP11B2CYP11B1CYP17A1NPY5RCYP2A6
SCHEMBL16282336 0.83 CYP11B2 (0.69) CYP11B2CYP11B1CYP17A1NPY5RCYP2A6
SCHEMBL1422898 0.83 CYP11B2 (0.70) CYP11B2CYP11B1CYP17A1NPY5RCYP3A4
SCHEMBL4511285 0.83 CYP11B2 (1.00) CYP11B2CYP11B1CYP17A1NPY5RCYP19A1
SCHEMBL24534338 0.82 CYP2A6 (0.88) CYP11B2CYP11B1CYP17A1CYP2A6CYP3A4
SCHEMBL29360677 0.82 CYP2A6 (0.88) CYP11B2CYP11B1CYP17A1CYP2A6CYP3A4
SCHEMBL13907273 0.82 CYP2A6 (0.88) CYP11B2CYP11B1CYP17A1CYP2A6CYP3A4
SCHEMBL22534558 0.81 CYP11B2 (0.66) CYP11B2CYP11B1CYP17A1NPY5RALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111902398-B Salts of URAT-1 inhibitors 益方生物科技(上海)股份有限公司 2024-01-26 CN claimed
CN-120028308-A Small molecule Raman probe, bar code probe, encoding method and application thereof 北京大学 2025-05-23 CN disclosed
CN-111902398-B Salts of URAT-1 inhibitors 益方生物科技(上海)股份有限公司 2024-01-26 CN disclosed