Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 16/20 | 0.80 |
| ▸ | IDO1 | P14902 | 16/20 | 0.80 |
| ▸ | IDO2 | Q6ZQW0 | 12/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | APAF1 | O14727 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.54 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17830810 | 0.91 | IDO1 (0.83) | TDO2IDO1IDO2KMT2AAPAF1 | |
| SCHEMBL31382841 | 0.91 | IDO1 (0.83) | TDO2IDO1IDO2KMT2AAPAF1 | |
| SCHEMBL9222306 | 0.89 | IDO1 (1.00) | TDO2IDO1IDO2KMT2AAPAF1 | |
| SCHEMBL9104095 | 0.89 | TDO2 (0.72) | TDO2IDO1IDO2KMT2AAPAF1 | |
| SCHEMBL30639061 | 0.88 | TDO2 (0.63) | TDO2IDO1IDO2KMT2AAPAF1 | |
| SCHEMBL26614153 | 0.88 | TDO2 (0.63) | TDO2IDO1IDO2KMT2AAPAF1 | |
| SCHEMBL12289968 | 0.85 | IDO1 (0.71) | TDO2IDO1IDO2KMT2AAPAF1 | |
| SCHEMBL26856831 | 0.85 | TDO2 (0.77) | TDO2IDO1IDO2KMT2AAPAF1 | |
| SCHEMBL24513483 | 0.83 | IDO1 (0.71) | TDO2IDO1IDO2KMT2AAPAF1 | |
| SCHEMBL12290107 | 0.83 | IDO1 (0.74) | TDO2IDO1IDO2KMT2AAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117298119-B | Application of tryptanthrin derivative in preparation of drug-resistant candida albicans drug | 云南中医药大学 | 2024-01-23 | — | — | CN | disclosed |
| CN-117298119-A | Application of tryptanthrin derivative in preparation of drug-resistant candida albicans drug | 云南中医药大学 | 2023-12-29 | — | — | CN | disclosed |