Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 14/20 | 0.71 |
| ▸ | TDO2 | P48775 | 10/20 | 0.71 |
| ▸ | IDO2 | Q6ZQW0 | 8/20 | 0.71 |
| ▸ | APAF1 | O14727 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26858212 | 0.86 | TDO2 (0.70) | IDO1TDO2IDO2APAF1KMT2A | |
| SCHEMBL26614091 | 0.85 | APAF1 (0.67) | IDO1TDO2IDO2APAF1KMT2A | |
| SCHEMBL26614136 | 0.85 | IDO1 (0.71) | IDO1TDO2IDO2APAF1KMT2A | |
| SCHEMBL21379735 | 0.83 | IDO1 (0.72) | IDO1TDO2IDO2APAF1KMT2A | |
| SCHEMBL9222306 | 0.83 | IDO1 (1.00) | IDO1TDO2IDO2APAF1KMT2A | |
| SCHEMBL30712754 | 0.83 | TDO2 (0.80) | IDO1TDO2IDO2APAF1KMT2A | |
| SCHEMBL4586093 | 0.82 | APAF1 (0.71) | IDO1TDO2IDO2APAF1KMT2A | |
| SCHEMBL30639074 | 0.82 | IDO1 (0.71) | IDO1TDO2IDO2APAF1KMT2A | |
| SCHEMBL26614220 | 0.82 | IDO1 (0.71) | IDO1TDO2IDO2APAF1KMT2A | |
| SCHEMBL30639101 | 0.82 | APAF1 (0.67) | IDO1TDO2IDO2APAF1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022122682-A2 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-06-16 | — | — | WO | disclosed |