Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 7/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ACACA | Q13085 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12896081 | 0.86 | GCK (0.45) | KMT2AACACBPARP10ALDH1A1ACACA | |
| SCHEMBL5266868 | 0.84 | DYRK1A (0.46) | ALDH1A1POLBDYRK1ACLK1DYRK1B | |
| SCHEMBL165125 | 0.78 | MAPK1 (0.57) | KMT2AACACBPARP10ABL1ALDH1A1 | |
| SCHEMBL30342167 | 0.78 | MEN1 (0.46) | KMT2ADYRK1ACLK1DYRK1B | |
| SCHEMBL104785 | 0.78 | ACACB (0.47) | KMT2AACACBPARP10ABL1ALDH1A1 | |
| SCHEMBL5649401 | 0.78 | KMT2A (0.55) | KMT2AACACBPARP10ALDH1A1KDM4E | |
| SCHEMBL711104 | 0.78 | KMT2A (0.55) | KMT2AACACBPARP10ALDH1A1KDM4E | |
| SCHEMBL30697569 | 0.78 | GPR88 (0.43) | — | |
| SCHEMBL15069756 | 0.77 | KDM4E (0.47) | ALDH1A1POLBKDM4ECYP2C19 | |
| SCHEMBL17963167 | 0.76 | PARP10 (0.56) | KMT2AACACBPARP10ALDH1A1ACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285516-A | Dehydrogenated phenyl achyranthis statin compound, preparation method and application thereof | 大连万众益生大健康有限公司 | 2023-12-26 | — | — | CN | disclosed |