Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 20/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31395578 | 0.82 | MAPK1 (0.48) | GPR88 | |
| SCHEMBL31395231 | 0.82 | GPR88 (0.47) | GPR88 | |
| SCHEMBL31395596 | 0.82 | GPR88 (0.43) | GPR88 | |
| SCHEMBL30713049 | 0.78 | KMT2A (0.39) | — | |
| SCHEMBL5266868 | 0.77 | DYRK1A (0.46) | — | |
| SCHEMBL15069756 | 0.76 | KDM4E (0.47) | — | |
| SCHEMBL569919 | 0.73 | P4HTM (0.66) | — | |
| SCHEMBL31740000 | 0.72 | GPR88 (0.45) | GPR88 | |
| SCHEMBL5524906 | 0.72 | L3MBTL1 (0.42) | — | |
| SCHEMBL31395314 | 0.71 | MAPT (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543857-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | ACADIA Pharmaceuticals Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| CN-119546577-A | Modulators of G protein-coupled receptor 88 | 阿卡蒂亚药品公司 | 2025-02-28 | — | — | CN | disclosed |
| WO-2023250060-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | ACADIA PHARMACEUTICALS INC. (US) | 2023-12-28 | — | — | WO | disclosed |