Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29277634 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2FPR2SIRT2RAB9ANPC1 | |
| SCHEMBL19739532 | 0.84 | FPR2 (0.43) | FPR2SIRT2RAB9ANPC1KMT2A | |
| SCHEMBL29806233 | 0.84 | FPR2 (0.43) | FPR2SIRT2RAB9ANPC1KMT2A | |
| SCHEMBL14738571 | 0.82 | ADORA2A (0.48) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL15819917 | 0.81 | NPSR1 (0.51) | FPR2RAB9ANPC1KMT2ATSHR | |
| SCHEMBL12492473 | 0.81 | HPGD (0.49) | FPR2SIRT2RAB9ANPC1KMT2A | |
| SCHEMBL2099046 | 0.79 | KDM4E (0.47) | SMN1; SMN2FPR2SIRT2RAB9ANPC1 | |
| SCHEMBL30982223 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL12492927 | 0.77 | FPR2 (0.42) | SMN1; SMN2FPR2SIRT2RAB9ANPC1 | |
| SCHEMBL13707719 | 0.77 | L3MBTL1 (0.43) | SMN1; SMN2FPR2SIRT2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4549438-A1 | FIVE-MEMBERED AND SIX-MEMBERED NITROGEN-CONTAINING COMPOUND, AND INTERMEDIATE, PREPARATION METHOD AND USE THEREOF | Hangzhou Synrx Therapeutics Biomedical Technology Co., Ltd. (CN) | 2025-05-07 | — | — | EP | disclosed |
| CN-117304183-A | Five-membered and six-membered nitrogen-containing compound, intermediate thereof, preparation method and application | 杭州圣域生物医药科技有限公司 | 2023-12-29 | — | — | CN | disclosed |