Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3061547 | 0.89 | POLB (0.46) | ALDH1A1KDM4EHTTHPGDSMN1; SMN2 | |
| SCHEMBL3056684 | 0.84 | KMT2A (0.46) | ALDH1A1HTTSMN1; SMN2EPHX2CYP2C9 | |
| SCHEMBL3078379 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL3066591 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4EHTTHPGDSMN1; SMN2 | |
| SCHEMBL3069102 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KDM4EHTTNPC1RAB9A | |
| SCHEMBL3062323 | 0.79 | KMT2A (0.60) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL3074125 | 0.78 | SMN1; SMN2 (0.43) | ALDH1A1KDM4EHTTHPGDSMN1; SMN2 | |
| SCHEMBL3080052 | 0.76 | KMT2A (0.50) | ALDH1A1HTTCYP2C9CYP2C19LMNA | |
| SCHEMBL5362137 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HTTSMN1; SMN2EPHX2CYP2C9 | |
| SCHEMBL3070972 | 0.72 | ALDH1A1 (0.43) | ALDH1A1KDM4EHTTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267555-A1 | Fungicidal mixtures II | BASF SE (DE) | 2010-10-21 | — | — | US | claimed |
| EP-2222169-A2 | FUNGICIDAL MIXTURES II | BASF SE (DE) | 2010-09-01 | — | — | EP | claimed |
| WO-2009063075-A2 | FUNGICIDAL MIXTURES II | BASF SE (DE) | 2009-05-22 | — | — | WO | claimed |
| US-20100267555-A1 | Fungicidal mixtures II | BASF SE (DE) | 2010-10-21 | — | — | US | disclosed |
| EP-2222169-A2 | FUNGICIDAL MIXTURES II | BASF SE (DE) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009063075-A2 | FUNGICIDAL MIXTURES II | BASF SE (DE) | 2009-05-22 | — | — | WO | disclosed |
| US-20050277663-A1 | 3-Aryl-3-hydroxy-and 3-aryl-3-oxopropionic acid esters as fungicides | ATP CAPITAL LP | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277663-A1 | 3-Aryl-3-hydroxy-and 3-aryl-3-oxopropionic acid esters as fungicides | CYP21A2, HAO1, AHR | ALDH1A1 99/4885KDM4E 1577/4885HTT 1369/4885 |
| US-20100267555-A1 | Fungicidal mixtures II | CBR3, CBR1, NOX3 | ALDH1A1 764/4885KDM4E 3692/4885HTT 1042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.