Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.55 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.45 |
| ▸ | ITGAL | P20701 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 5/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30713653 | 0.83 | GPR84 (0.58) | GPR84METMTNR1AITGB2ICAM1 | |
| SCHEMBL30713622 | 0.78 | GPR84 (0.46) | GPR84METMTNR1ALRRK2AXL | |
| SCHEMBL27252804 | 0.75 | GPR84 (0.67) | GPR84METMTNR1AITGB2ICAM1 | |
| SCHEMBL18181377 | 0.75 | GPR84 (0.67) | GPR84METMTNR1AITGB2ICAM1 | |
| SCHEMBL24301144 | 0.75 | SMN1; SMN2 (0.61) | GPR84METMTNR1AITGB2ICAM1 | |
| SCHEMBL858027 | 0.74 | GPR84 (0.61) | GPR84METMTNR1AITGB2ICAM1 | |
| SCHEMBL2217980 | 0.74 | GPR84 (0.76) | GPR84METMTNR1ADRD4DRD2 | |
| SCHEMBL6091363 | 0.74 | GPR84 (0.56) | GPR84METMTNR1AITGB2ICAM1 | |
| SCHEMBL1176817 | 0.73 | GPR84 (0.59) | GPR84METMTNR1AITGB2ICAM1 | |
| SCHEMBL878881 | 0.73 | GPR84 (0.59) | GPR84METMTNR1ADRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295746-A | HPK1 inhibitor and application thereof in medicine | 贝达药业股份有限公司 | 2023-12-26 | — | — | CN | disclosed |