Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30713580 | 0.88 | CYP3A4 (0.39) | CYP3A4CYP2D6CYP2C9CYP2C19ALOX15 | |
| SCHEMBL30713578 | 0.87 | CYP3A4 (0.43) | CYP3A4CYP2D6CYP2C9CYP2C19CTSS | |
| SCHEMBL30713478 | 0.84 | CYP3A4 (0.41) | CYP3A4CYP2D6CYP2C9CYP2C19CTSS | |
| SCHEMBL30713496 | 0.79 | CYP3A4 (0.40) | CYP3A4CYP2D6CYP2C9CYP2C19CTSS | |
| SCHEMBL3315239 | 0.78 | CYP3A4 (0.47) | CYP3A4CYP2D6CYP2C9CYP2C19ALOX15 | |
| SCHEMBL7391113 | 0.73 | CYP3A4 (0.44) | CYP3A4CYP2D6CYP2C9CYP2C19CTSS | |
| SCHEMBL21640024 | 0.73 | CYP3A4 (0.44) | CYP3A4CYP2D6CYP2C9CYP2C19CTSS | |
| SCHEMBL14684169 | 0.72 | CYP3A4 (0.44) | CYP3A4CYP2D6CYP2C9CYP2C19CTSS | |
| SCHEMBL30713596 | 0.71 | MEN1 (0.34) | CA12CA1CA7CA14MEN1 | |
| SCHEMBL3834657 | 0.69 | OPRM1 (0.45) | CYP3A4CYP2D6CYP2C9CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547656-A1 | INDAZOLE COMPOUNDS | Tyra Biosciences, Inc. (US) | 2025-05-07 | — | — | EP | disclosed |
| WO-2024006897-A1 | INDAZOLE COMPOUNDS | TYRA BIOSCIENCES, INC. (US) | 2024-01-04 | — | — | WO | disclosed |