SCHEMBL30713596

SCHEMBL30713596

CC(C)(C)OC(=O)NC1(CCS(C)(=O)=O)CNC1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
MAPK1 P28482 1/20 0.34
KMT2A Q03164 1/20 0.34
CA12 O43570 4/20 0.33
CA14 Q9ULX7 4/20 0.33
CA1 P00915 2/20 0.33
CA7 P43166 2/20 0.33
CA2 P00918 1/20 0.33
CTSL P07711 1/20 0.32
P2RX7 Q99572 1/20 0.31
APLNR P35414 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20296850 0.79 MEN1 (0.39) MEN1MAPK1KMT2ACA12CA14
Hydrochloric Acid SCHEMBL23043372 0.77 KMT2A (0.38) MEN1MAPK1KMT2ACA12CA14
SCHEMBL584829 0.75 CA12 (0.36) MEN1MAPK1KMT2ACA12CA14
SCHEMBL2679884 0.74 CA12 (0.37) MEN1MAPK1KMT2ACA12CA14
SCHEMBL30713657 0.71 CYP3A4 (0.40) MEN1KMT2ACA12CA14CA1
SCHEMBL14813442 0.71 CA12 (0.33) MEN1MAPK1KMT2ACA12CA14
SCHEMBL18530347 0.71 TDP1 (0.36) MEN1MAPK1KMT2ACTSLP2RX7
SCHEMBL16993451 0.71 TDP1 (0.36) MEN1MAPK1KMT2ACTSLP2RX7
SCHEMBL10799485 0.71 TDP1 (0.40) MEN1MAPK1KMT2ACA12CA14
SCHEMBL3942864 0.71 P2RX7 (0.34) MEN1MAPK1KMT2ACA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547656-A1 INDAZOLE COMPOUNDS Tyra Biosciences, Inc. (US) 2025-05-07 EP disclosed
CN-119731165-A Indazole compounds 泰拉生物科学公司 2025-03-28 CN disclosed
WO-2024006897-A1 INDAZOLE COMPOUNDS TYRA BIOSCIENCES, INC. (US) 2024-01-04 WO disclosed