Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22322587 | 0.77 | LMNA (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4769775 | 0.75 | KDM5B (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31316179 | 0.72 | TSHR (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4763799 | 0.72 | TSHR (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10877795 | 0.70 | KDM4E (0.41) | — | |
| SCHEMBL25863831 | 0.70 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL10877791 | 0.70 | KDM5B (0.34) | — | |
| SCHEMBL161461 | 0.69 | CA12 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31358932 | 0.66 | CA12 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17294253 | 0.64 | HSD17B10 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018157-A1 | CYCLIC COMPOUNDS AND METHODS OF USING SAME | SCHRÖDINGER, INC. | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018157-A1 | CYCLIC COMPOUNDS AND METHODS OF USING SAME | MALT1, FKBP1B, FKBP1A | CA12 391/4885CA1 142/4885CA2 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.