Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.69 |
| ▸ | RAB9A | P51151 | 9/20 | 0.69 |
| ▸ | NPC1 | O15118 | 9/20 | 0.69 |
| ▸ | MAPT | P10636 | 8/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | GLA | P06280 | 4/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.69 |
| ▸ | GAA | P10253 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 3/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | PPARG | P37231 | 1/20 | 0.69 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.69 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.69 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30466258 | 1.00 | KDM4E (0.69) | KDM4ERAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL30714873 | 0.89 | KDM4E (0.74) | KDM4ERAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL9293186 | 0.89 | KDM4E (0.74) | KDM4ERAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL25288484 | 0.87 | KDM4E (0.71) | KDM4ERAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL8373442 | 0.86 | MAPT (0.68) | KDM4ERAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL4592655 | 0.86 | KDM4E (0.64) | KDM4ERAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL11325434 | 0.86 | MAPT (0.64) | KDM4ERAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL11193289 | 0.86 | RAB9A (0.66) | KDM4ERAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL12471564 | 0.86 | KDM4E (0.64) | KDM4ERAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL30466256 | 0.86 | MAPT (0.68) | KDM4ERAB9ANPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140378515-A1 | IMMUNOSUPPRESSIVE COMPOUNDS | MESAIK MUHAMMAD A (PK) | 2014-12-25 | — | — | US | claimed |
| WO-2012108689-A2 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR | 부산대학교 산학협력단 (KR) | 2012-08-16 | — | — | WO | claimed |
| WO-2023133875-A1 | MULTIFUNCTIONAL GROUP METAL CORROSION INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 嘉庚创新实验室 | 2023-07-20 | — | — | WO | disclosed |
| CN-116217513-A | Preparation method of 2' -substituted benzothiazole | 重庆工商大学 | 2023-06-06 | — | — | CN | disclosed |
| US-20150366776-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PUSAN NAT UNIV IND COOP FOUND (KR) | 2015-12-24 | — | — | US | disclosed |
| US-9155690-B2 | Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use thereof | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2015-10-13 | — | — | US | disclosed |
| US-8889881-B2 | Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use therefor | Pusan National University Industry —University Cooperation Foundation (KR) | 2014-11-18 | — | — | US | disclosed |
| US-20140037564-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR | Pusan National University Indusrtyuniversity (KR) | 2014-02-06 | — | — | US | disclosed |
| WO-2012108689-A2 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR | 부산대학교 산학협력단 (KR) | 2012-08-16 | — | — | WO | disclosed |
| EP-2218464-A1 | Compounds for non-invasive measurement of aggregates of amyloid peptides | Technische Universität München (DE) | 2010-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150366776-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PPARG, PPARA, TYR | KDM4E 3430/4885RAB9A 3882/4885NPC1 3522/4885 |
| US-20140378515-A1 | IMMUNOSUPPRESSIVE COMPOUNDS | IL4, TLR4, NOX4 | KDM4E 69/4885RAB9A 2337/4885NPC1 3004/4885 |
| US-20140037564-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR | PPARG, PPARA, PPARD | KDM4E 3588/4885RAB9A 4420/4885NPC1 3207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.