SCHEMBL30715262

SCHEMBL30715262

Cc1ccc2[nH]c3cccc(C)c3c2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.54
NPC1 O15118 3/20 0.54
MEN1 O00255 2/20 0.54
POLB P06746 1/20 0.54
KIF11 P52732 4/20 0.52
MAPT P10636 4/20 0.49
ALDH1A1 P00352 3/20 0.49
KDM4E B2RXH2 3/20 0.49
HPGD P15428 2/20 0.49
HSD17B10 Q99714 2/20 0.49
ALOX15 P16050 1/20 0.49
GABRP O00591 2/20 0.47
GABRD O14764 2/20 0.47
GABRA1 P14867 2/20 0.47
GABRB1 P18505 2/20 0.47
GABRG2 P18507 2/20 0.47
GABRB3 P28472 2/20 0.47
GABRA5 P31644 2/20 0.47
GABRA3 P34903 2/20 0.47
GABRA2 P47869 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21165684 1.00 KMT2A (0.54) KMT2ANPC1MEN1POLBKIF11
SCHEMBL22514642 0.85 KIF11 (0.61) KMT2ANPC1MEN1POLBKIF11
SCHEMBL29726992 0.85 KIF11 (0.61) KMT2ANPC1MEN1POLBKIF11
SCHEMBL29022539 0.84 CHEK1 (0.50) KMT2ANPC1MEN1POLBKIF11
SCHEMBL21972721 0.83 MEN1 (0.66) KMT2ANPC1MEN1POLBKIF11
SCHEMBL28937473 0.82 GABRP (0.48) KMT2ANPC1MEN1KIF11MAPT
SCHEMBL30573128 0.80 MEN1 (0.62) KMT2AMEN1KIF11MAPTALDH1A1
SCHEMBL2991387 0.80 MEN1 (0.62) KMT2AMEN1KIF11MAPTALDH1A1
SCHEMBL16810761 0.80 CDK4 (0.55) KMT2AMEN1KIF11MAPTKDM4E
SCHEMBL29150376 0.79 MAPT (0.60) KMT2AMEN1KIF11MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117402102-A Diamine containing carbazole moieties and polyimide gas separation membrane prepared from diamine and method 西北工业大学 2024-01-16 CN claimed
CN-117402102-A Diamine containing carbazole moieties and polyimide gas separation membrane prepared from diamine and method 西北工业大学 2024-01-16 CN disclosed