Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.44 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561293 | 0.87 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNANPC1RAB9AGAA | |
| SCHEMBL26716442 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNANPC1RAB9AGAA | |
| SCHEMBL3705474 | 0.83 | RAB9A (0.67) | SMN1; SMN2LMNANPC1RAB9AHTT | |
| SCHEMBL17887994 | 0.80 | SMN1; SMN2 (0.77) | SMN1; SMN2LMNANPC1RAB9AGAA | |
| SCHEMBL10494518 | 0.79 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNANPC1RAB9AGAA | |
| SCHEMBL11335644 | 0.78 | HPGD (0.51) | LMNAHTTMEN1KMT2AHPGD | |
| SCHEMBL31477865 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNANPC1RAB9AGAA | |
| SCHEMBL8087947 | 0.77 | SMN1; SMN2 (0.62) | SMN1; SMN2HTT | |
| SCHEMBL18383667 | 0.76 | KMT2A (0.51) | SMN1; SMN2LMNANPC1RAB9AGAA | |
| SCHEMBL496789 | 0.75 | SMN1; SMN2 (0.81) | SMN1; SMN2LMNANPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592738-B1 | RESIN COMPOSITIONS | CIBA HOLDING INC (CH) | 2020-07-29 | — | — | EP | disclosed |
| US-7790793-B2 | Amide nucleating agent compositions | CIBA SPECIALTY CHEM. CORP. (US) | 2010-09-07 | — | — | US | disclosed |
| CN-100344681-C | Resin compositions | CIBA SC HOLDING AG (CH) | 2007-10-24 | — | — | CN | disclosed |
| US-20070149663-A1 | Resin compositions | CIBA SPECIALTY CHEMICALS CORP. | 2007-06-28 | — | — | US | disclosed |
| CN-1747995-A | Resin compositions | CIBA SC HOLDING AG (CH) | 2006-03-15 | — | — | CN | disclosed |
| EP-1592738-A2 | RESIN COMPOSITIONS | Ciba SC Holding AG (CH) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004072168-A2 | RESIN COMPOSITIONS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-08-26 | — | — | WO | disclosed |