Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.81 |
| ▸ | NPC1 | O15118 | 4/20 | 0.81 |
| ▸ | RAB9A | P51151 | 4/20 | 0.81 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.69 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | NAAA | Q02083 | 1/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.57 |
| ▸ | GRM5 | P41594 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | CTSG | P08311 | 1/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.54 |
| ▸ | CMA1 | P23946 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17225741 | 0.93 | SMN1; SMN2 (0.77) | SMN1; SMN2NPC1RAB9AEPHX2KCNA5 | |
| SCHEMBL17887994 | 0.90 | SMN1; SMN2 (0.77) | SMN1; SMN2NPC1RAB9AEPHX2KCNA5 | |
| SCHEMBL1927508 | 0.90 | NPC1 (1.00) | SMN1; SMN2NPC1RAB9AEPHX2KCNA5 | |
| SCHEMBL10137831 | 0.89 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AEPHX2KCNA5 | |
| SCHEMBL12650598 | 0.88 | NAAA (0.66) | SMN1; SMN2NPC1RAB9AEPHX2KCNA5 | |
| SCHEMBL10099547 | 0.86 | NAAA (0.69) | SMN1; SMN2NPC1RAB9AEPHX2KCNA5 | |
| SCHEMBL1927498 | 0.86 | SMN1; SMN2 (0.76) | SMN1; SMN2NPC1RAB9AEPHX2KCNA5 | |
| SCHEMBL3638357 | 0.86 | GRM5 (0.73) | SMN1; SMN2NPC1RAB9AEPHX2KCNA5 | |
| SCHEMBL8851563 | 0.86 | EPHX2 (0.65) | SMN1; SMN2NPC1RAB9AEPHX2KCNA5 | |
| SCHEMBL27389698 | 0.86 | EPHX2 (0.65) | SMN1; SMN2NPC1RAB9AEPHX2KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911645-B1 | 5-MEMBERED HETEROARYL COMPOUNDS CONTAINING A HYDROXAMATE MOIETY AND THEIR USE | UNIV LILLE (FR) | 2022-12-07 | — | — | EP | claimed |
| WO-2008093064-A1 | L-ALANINE DERIVATIVES AS α5 BETA 1 ANTAGONISTS | ASTRAZENECA AB (SE) | 2008-08-07 | — | — | WO | claimed |
| US-20080182842-A1 | L-alanine derivatives as a5beta1 antagonists | ASTRAZENECA AB (SE) | 2008-07-31 | — | — | US | claimed |
| EP-1497261-A1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2005-01-19 | — | — | EP | claimed |
| WO-2003091204-A1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-11-06 | — | — | WO | claimed |
| WO-2003047572-A1 | USE OF 1-PHENYL-OXAZOLIDINE-2-ONE COMPOUNDS AS PROTEASE M INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-12 | — | — | WO | claimed |
| US-20260068882-A1 | ARTHROPOD CONTROLLING COMPOSITION | FIRMENICH & CIE (CH) | 2026-03-12 | — | — | US | disclosed |
| CN-119504643-A | 3- (2-Aminobenzo [ d ] thiazol-5-yl) benzamide derivative and preparation method and application thereof | 贵州省天然产物研究中心 | 2025-02-25 | — | — | CN | disclosed |
| CN-118480001-A | C-Kit (V559D)/PDGFR beta double-target allosteric inhibitor and preparation method, pharmaceutical composition and application thereof | 贵州省天然产物研究中心 | 2024-08-13 | — | — | CN | disclosed |
| CN-113873884-B | Arthropod control composition | 弗门尼舍有限公司 | 2024-06-14 | — | — | CN | disclosed |
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| CN-116253686-B | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-11-17 | — | — | CN | disclosed |
| US-20230357158-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2023-11-09 | — | — | US | disclosed |
| US-20080182842-A1 | L-alanine derivatives as a5beta1 antagonists | ASTRAZENECA AB (SE) | 2008-07-31 | — | — | US | disclosed |
| EP-1701956-A1 | PYRROLO[2,3-B]PYRIDINE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | Pfizer Italia S.r.l. (IT) | 2006-09-20 | — | — | EP | disclosed |
| CN-1753670-A | Novel derivatives of benzimidazole and imidazo-pyridine and their use as medicaments | SOD CONSEILS RECH APPLIC (FR) | 2006-03-29 | — | — | CN | disclosed |
| US-20050256151-A1 | Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them | PHARMACIA ITALIA S.P.A. (IT) | 2005-11-17 | — | — | US | disclosed |
| WO-2005063746-A1 | PYRROLO[2,3-b]PYRIDINE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PFIZER ITALIA S.R.L. (IT) | 2005-07-14 | — | — | WO | disclosed |
| EP-1497261-A1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003091204-A1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260068882-A1 | ARTHROPOD CONTROLLING COMPOSITION | CNOT9, MSL1, MT-CO2 | SMN1; SMN2 2293/4885NPC1 1270/4885RAB9A 77/4885 |
| US-20050256151-A1 | Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them | MAP3K6, MAP3K3, MAP3K1 | SMN1; SMN2 1459/4885NPC1 3315/4885RAB9A 1269/4885 |
| US-11873291-B2 | Quinoline cGAS antagonist compounds | CGAS, GLS2, GLS | SMN1; SMN2 2633/4885NPC1 667/4885RAB9A 2346/4885 |
| US-20080182842-A1 | L-alanine derivatives as a5beta1 antagonists | ITGB1, ITGA2B, ITGB5 | SMN1; SMN2 1605/4885NPC1 3892/4885RAB9A 1382/4885 |
| US-20230357158-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | CGAS, GLS2, GLS | SMN1; SMN2 2633/4885NPC1 667/4885RAB9A 2346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.