Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6119560 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAPOLBGBA2GAA | |
| SCHEMBL3392894 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAPOLBGBA2GAA | |
| SCHEMBL17801630 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAPOLBGBA2GAA | |
| SCHEMBL29838376 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAPOLBGBA2GAA | |
| SCHEMBL31372353 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAPOLBGBA2GAA | |
| SCHEMBL3708900 | 0.81 | LMNA (0.54) | SMN1; SMN2LMNAPOLBGBA2GAA | |
| SCHEMBL3652388 | 0.81 | LMNA (0.54) | SMN1; SMN2LMNAPOLBGBA2GAA | |
| SCHEMBL3652385 | 0.81 | LMNA (0.54) | SMN1; SMN2LMNAPOLBGBA2GAA | |
| SCHEMBL25350252 | 0.81 | LMNA (0.48) | SMN1; SMN2LMNAPOLBGBA2GAA | |
| SCHEMBL18498621 | 0.80 | LMNA (0.56) | SMN1; SMN2LMNAPOLBGBA2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175024-A1 | NEW FUSED HETEROCYCLIC COMPOUND AS CDKS INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2024-08-29 | — | — | WO | disclosed |
| WO-2023227125-A1 | NEW FUSED-HETEROCYCLIC COMPOUND AS CDK INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2023-11-30 | — | — | WO | disclosed |