Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 3/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.54 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.54 |
| ▸ | CCNK | O75909 | 15/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 15/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 11/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 11/20 | 0.42 |
| ▸ | CDK2 | P24941 | 11/20 | 0.42 |
| ▸ | CDK9 | P50750 | 11/20 | 0.42 |
| ▸ | CDK7 | P50613 | 11/20 | 0.42 |
| ▸ | CCNH | P51946 | 11/20 | 0.42 |
| ▸ | MNAT1 | P51948 | 9/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26697091 | 1.00 | CLK1 (0.54) | CLK1CDK5CDK5R1CCNKCDK12 | |
| SCHEMBL26697038 | 0.85 | CLK1 (0.59) | CLK1CDK5CDK5R1CCNKCDK12 | |
| SCHEMBL30716301 | 0.85 | CLK1 (0.59) | CLK1CDK5CDK5R1CCNKCDK12 | |
| SCHEMBL24900493 | 0.82 | TDO2 (0.47) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL30957590 | 0.82 | TDO2 (0.47) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL21629046 | 0.81 | CCNK (0.44) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL30554768 | 0.81 | CCNK (0.44) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL21178668 | 0.81 | CLK1 (0.50) | CLK1CDK5CDK5R1CCNKCDK12 | |
| SCHEMBL21184587 | 0.81 | CCNK (0.42) | CLK1CDK5CDK5R1CCNKCDK12 | |
| SCHEMBL30260854 | 0.81 | CLK1 (0.50) | CLK1CDK5CDK5R1CCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023227125-A1 | NEW FUSED-HETEROCYCLIC COMPOUND AS CDK INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2023-11-30 | — | — | WO | disclosed |