SCHEMBL30716583

SCHEMBL30716583

CCOC(=O)c1ccccc1C(=O)OOC(C)CC

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.66
ALDH1A1 P00352 8/20 0.53
HSD17B10 Q99714 4/20 0.53
CDC25B P30305 1/20 0.49
KDM4E B2RXH2 5/20 0.47
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HPGD P15428 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CYP3A4 P08684 2/20 0.46
CA2 P00918 1/20 0.46
MAPK1 P28482 2/20 0.45
TP53 P04637 1/20 0.45
LMNA P02545 1/20 0.44
PRSS1 P07477 1/20 0.43
PRSS2 P07478 1/20 0.43
PRSS3 P35030 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28360489 1.00 TSHR (0.66) TSHRALDH1A1HSD17B10CDC25BKDM4E
SCHEMBL30766153 0.92 TSHR (0.50) TSHRALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL29124279 0.86 ALDH1A1 (0.54) TSHRALDH1A1HSD17B10KDM4ETDP1
SCHEMBL28815185 0.84 TSHR (0.70) TSHRALDH1A1HSD17B10CDC25BKDM4E
SCHEMBL9492898 0.83 TSHR (0.88) TSHRALDH1A1HSD17B10CDC25BKDM4E
Diethyl Phthalate SCHEMBL22296 0.81 TSHR (1.00) TSHRALDH1A1HSD17B10CDC25BKDM4E
Diethyl Phthalate SCHEMBL5306972 0.81 TSHR (1.00) TSHRALDH1A1HSD17B10CDC25BKDM4E
Diethyl Phthalate SCHEMBL29404255 0.81 TSHR (1.00) TSHRALDH1A1HSD17B10CDC25BKDM4E
SCHEMBL9067288 0.80 TSHR (0.81) TSHRALDH1A1HSD17B10CDC25BKDM4E
Diethyl Phthalate SCHEMBL19252611 0.79 TSHR (0.95) TSHRALDH1A1HSD17B10CDC25BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117233275-A Pretreatment and trace measurement method for measuring plasticizer in DHA crude oil 青岛琅琊台集团股份有限公司 2023-12-15 CN disclosed