Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24667671 | 1.00 | PDGFRB (0.36) | PDGFRBPDGFRATUBB1ALDH1A1KDM4E | |
| SCHEMBL27278144 | 0.82 | ALDH1A1 (0.41) | TUBB1ALDH1A1KDM4ETDP1P2RX3 | |
| SCHEMBL24667673 | 0.81 | PDE4A (0.37) | PDGFRBPDGFRATUBB1P2RX3P2RX2 | |
| Hydrochloric Acid SCHEMBL9687781 | 0.81 | ALDH1A1 (0.43) | TUBB1ALDH1A1KDM4ETDP1P2RX3 | |
| SCHEMBL30716907 | 0.79 | NPC1 (0.38) | ALDH1A1KDM4ETDP1P2RX3P2RX2 | |
| SCHEMBL6607812 | 0.79 | NPC1 (0.38) | ALDH1A1KDM4ETDP1P2RX3P2RX2 | |
| SCHEMBL9356583 | 0.76 | ALDH1A1 (0.36) | PDGFRBPDGFRATUBB1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL10583938 | 0.76 | ALDH1A1 (0.39) | TUBB1ALDH1A1KDM4ETDP1TUBB4A | |
| SCHEMBL6606565 | 0.75 | ALDH1A1 (0.33) | TUBB1ALDH1A1KDM4ETDP1TUBB4A | |
| Hydrochloric Acid SCHEMBL9526541 | 0.74 | ALDH1A1 (0.38) | TUBB1ALDH1A1KDM4ETDP1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117412960-A | Isoindolinone compounds and imaging agents for imaging huntingtin | CHDI基金会股份有限公司 | 2024-01-16 | — | — | CN | disclosed |