Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607812 | 1.00 | NPC1 (0.38) | NPC1GAATTRALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL10583938 | 0.85 | ALDH1A1 (0.39) | NPC1GAATTRALDH1A1MAPT | |
| SCHEMBL12467200 | 0.85 | PGK1 (0.40) | NPC1GAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL27278144 | 0.84 | ALDH1A1 (0.41) | NPC1TTRALDH1A1MAPTPOLB | |
| Hydrochloric Acid SCHEMBL9687781 | 0.82 | ALDH1A1 (0.43) | NPC1GAATTRALDH1A1MAPT | |
| SCHEMBL24667671 | 0.79 | PDGFRB (0.36) | ALDH1A1MAPTL3MBTL1CYP2C19KDM4E | |
| SCHEMBL30716893 | 0.79 | PDGFRB (0.36) | ALDH1A1MAPTL3MBTL1CYP2C19KDM4E | |
| SCHEMBL15142051 | 0.78 | GAA (0.42) | GAAALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL24529326 | 0.78 | HTR1A (0.43) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9356583 | 0.77 | ALDH1A1 (0.36) | NPC1ALDH1A1MAPTPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117412960-A | Isoindolinone compounds and imaging agents for imaging huntingtin | CHDI基金会股份有限公司 | 2024-01-16 | — | — | CN | disclosed |