Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 13/20 | 0.57 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ATR | Q13535 | 2/20 | 0.48 |
| ▸ | ATRIP | Q8WXE1 | 2/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27029526 | 1.00 | PIK3CA (0.57) | PIK3CAMAP3K12MAPTTSHRMAPK1 | |
| SCHEMBL27062781 | 0.89 | CHRNB2 (0.52) | PIK3CAMAP3K12MAPTTSHRMAPK1 | |
| SCHEMBL30718212 | 0.81 | CHRNB2 (0.51) | PIK3CAMAPK1HSD17B10CHRNB2CHRNA4 | |
| SCHEMBL27029561 | 0.81 | CHRNB2 (0.51) | PIK3CAMAPK1HSD17B10CHRNB2CHRNA4 | |
| SCHEMBL10327965 | 0.80 | PIK3CA (0.74) | PIK3CAMAP3K12PIK3CB | |
| SCHEMBL30718239 | 0.78 | CHRNB2 (0.53) | PIK3CAPIK3CBCHRNB2CHRNA4 | |
| SCHEMBL27029440 | 0.78 | CHRNB2 (0.53) | PIK3CAPIK3CBCHRNB2CHRNA4 | |
| SCHEMBL27029450 | 0.78 | CYP1A2 (0.55) | PIK3CAMAPTTSHRMAPK1HSD17B10 | |
| SCHEMBL30718177 | 0.78 | CYP1A2 (0.55) | PIK3CAMAPTTSHRMAPK1HSD17B10 | |
| SCHEMBL29931687 | 0.78 | CHRNB2 (0.48) | PIK3CAMAPTTSHRCHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117157284-A | CTLA-4 small molecule degradation agent and application thereof | 苏州国匡医药科技有限公司 | 2023-12-01 | — | — | CN | disclosed |