Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.58 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.52 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27029498 | 1.00 | CFTR (0.58) | CFTRSMPD3ACHEGPR119TBK1 | |
| SCHEMBL30718196 | 0.87 | GPR119 (0.54) | CFTRSMPD3ACHEGPR119TBK1 | |
| SCHEMBL27029500 | 0.87 | GPR119 (0.54) | CFTRSMPD3ACHEGPR119TBK1 | |
| SCHEMBL29931553 | 0.86 | KDM4E (0.52) | CFTRCA2CA9MTORMEN1 | |
| SCHEMBL3651086 | 0.84 | ACHE (0.57) | ACHEGPR119TBK1CHRNA7DDB1 | |
| SCHEMBL8514838 | 0.83 | ACHE (0.51) | ACHEGPR119TBK1CHRNA7CA2 | |
| SCHEMBL8511601 | 0.83 | ACHE (0.47) | CFTRACHEGPR119TBK1CHRNA7 | |
| SCHEMBL8515547 | 0.83 | ACHE (0.47) | CFTRACHEGPR119TBK1CHRNA7 | |
| SCHEMBL3274585 | 0.83 | ACHE (0.66) | ACHEGPR119TBK1CHRNA7DDB1 | |
| SCHEMBL30831452 | 0.82 | ACHE (0.57) | ACHEGPR119CHRNA7DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117157284-A | CTLA-4 small molecule degradation agent and application thereof | 苏州国匡医药科技有限公司 | 2023-12-01 | — | — | CN | disclosed |