Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.62 |
| ▸ | KDM1A | O60341 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ME3 | Q16798 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15055182 | 1.00 | EPHX2 (0.62) | EPHX2KDM1ASIGMAR1MEN1KMT2A | |
| SCHEMBL34468338 | 1.00 | EPHX2 (0.62) | EPHX2KDM1ASIGMAR1MEN1KMT2A | |
| SCHEMBL34468288 | 0.91 | ALDH1A1 (0.68) | EPHX2KDM1ASIGMAR1MEN1KMT2A | |
| SCHEMBL5801183 | 0.91 | EPHX2 (0.72) | EPHX2KDM1ASIGMAR1MEN1KMT2A | |
| SCHEMBL4693545 | 0.90 | EPHX2 (0.71) | EPHX2SIGMAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL24342370 | 0.87 | EPHX2 (0.65) | EPHX2SIGMAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL34468348 | 0.85 | SIGMAR1 (0.52) | KDM1ASIGMAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL34468354 | 0.85 | SIGMAR1 (0.52) | EPHX2KDM1ASIGMAR1MEN1KMT2A | |
| SCHEMBL15054874 | 0.85 | SIGMAR1 (0.52) | KDM1ASIGMAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL21626178 | 0.84 | KDM1A (0.49) | EPHX2KDM1AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547247-A2 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2025-05-07 | — | — | EP | disclosed |
| WO-2024006956-A9 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-04-11 | — | — | WO | disclosed |
| WO-2024006956-A2 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-01-04 | — | — | WO | disclosed |