Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 8/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | BRD4 | O60885 | 4/20 | 0.43 |
| ▸ | BRD2 | P25440 | 3/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.43 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420243 | 0.85 | ABL1 (0.52) | ABL1MAP4K1SNCADYRK1AKIT | |
| SCHEMBL31420215 | 0.85 | ABL1 (0.52) | ABL1MAP4K1SNCADYRK1AKIT | |
| SCHEMBL17631568 | 0.85 | NPC1 (0.43) | ABL1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL17631569 | 0.85 | NPC1 (0.43) | ABL1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL17632001 | 0.81 | NPC1 (0.42) | ABL1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL30271964 | 0.81 | NPC1 (0.42) | ABL1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL17631999 | 0.81 | NPC1 (0.42) | ABL1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL30248327 | 0.81 | KMT2A (0.47) | ABL1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL30248351 | 0.81 | RAB9A (0.42) | ABL1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL30718469 | 0.81 | RAB9A (0.42) | ABL1RAB9AMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547247-A2 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2025-05-07 | — | — | EP | disclosed |
| WO-2024006956-A9 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-04-11 | — | — | WO | disclosed |
| WO-2024006956-A2 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-01-04 | — | — | WO | disclosed |