Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 9/20 | 0.52 |
| ▸ | MAP4K1 | Q92918 | 8/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420215 | 1.00 | ABL1 (0.52) | ABL1MAP4K1ROCK2SNCADYRK1A | |
| SCHEMBL31420229 | 0.92 | ABL1 (0.55) | ABL1MAP4K1KITPDGFRA | |
| SCHEMBL30718495 | 0.85 | ABL1 (0.45) | ABL1MAP4K1SNCADYRK1AKIT | |
| SCHEMBL31420241 | 0.81 | UCHL1 (0.47) | ABL1MAP4K1ROCK2ADORA2A | |
| SCHEMBL31420247 | 0.81 | UCHL1 (0.47) | ABL1MAP4K1ROCK2ADORA2A | |
| SCHEMBL31420273 | 0.80 | CHEK1 (0.43) | ABL1SNCADYRK1AKITPDGFRA | |
| SCHEMBL31420310 | 0.78 | ABL1 (0.48) | ABL1MAP4K1ROCK2ADORA2A | |
| SCHEMBL31420255 | 0.78 | ABL1 (0.48) | ABL1MAP4K1ROCK2ADORA2A | |
| SCHEMBL27311843 | 0.76 | GAA (0.57) | SNCADYRK1A | |
| SCHEMBL31166692 | 0.74 | ABL1 (0.65) | ABL1SNCADYRK1AKITPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119528901-B | Thiazole compound, dessumo and/or deubiquitinase inhibitor, and preparation methods and applications thereof | Shanghai tongji hospital (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-119528901-A | Thiazole compound, dessumo and/or deubiquitinase inhibitor, and preparation methods and applications thereof | 上海市同济医院 | 2025-02-28 | — | — | CN | disclosed |