Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.36 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27144904 | 1.00 | HCRTR1 (0.38) | HCRTR1HCRTR2HTR3APDE10ATLR4 | |
| SCHEMBL31413368 | 0.84 | MTOR (0.40) | HCRTR1HCRTR2HTR3APDE10ATLR4 | |
| SCHEMBL27145054 | 0.84 | MTOR (0.40) | HCRTR1HCRTR2HTR3APDE10ATLR4 | |
| SCHEMBL27144025 | 0.83 | HTR3A (0.40) | HCRTR1HCRTR2HTR3APDE10AHRH4 | |
| SCHEMBL31413461 | 0.83 | HTR3A (0.40) | HCRTR1HCRTR2HTR3APDE10AHRH4 | |
| SCHEMBL30718776 | 0.81 | HTR3A (0.38) | HCRTR1HCRTR2HTR3APDE10ATLR4 | |
| SCHEMBL27138967 | 0.81 | TLR4 (0.36) | HCRTR1HCRTR2HTR3APDE10ATLR4 | |
| SCHEMBL27138608 | 0.81 | HTR3A (0.38) | HCRTR1HCRTR2HTR3APDE10ATLR4 | |
| SCHEMBL31413439 | 0.79 | HCRTR2 (0.46) | HCRTR1HCRTR2HTR3APDE10AHRH4 | |
| SCHEMBL27152248 | 0.79 | HCRTR2 (0.46) | HCRTR1HCRTR2HTR3APDE10AHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547658-A1 | WEE1 DEGRADING COMPOUNDS AND USES THEREOF | Bristol-Myers Squibb Company (US) | 2025-05-07 | — | — | EP | disclosed |
| CN-119325469-A | WEE1 degrading compounds and uses thereof | 百时美施贵宝公司 | 2025-01-17 | — | — | CN | disclosed |
| WO-2024006881-A1 | WEE1 DEGRADING COMPOUNDS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-04 | — | — | WO | disclosed |