Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 9/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27145054 | 1.00 | MTOR (0.40) | MTORHTR3AHCRTR1HCRTR2PIK3CA | |
| SCHEMBL27144025 | 0.93 | HTR3A (0.40) | MTORHTR3AHCRTR1HCRTR2PDE10A | |
| SCHEMBL31413461 | 0.93 | HTR3A (0.40) | MTORHTR3AHCRTR1HCRTR2PDE10A | |
| SCHEMBL30718688 | 0.84 | HCRTR1 (0.38) | HTR3AHCRTR1HCRTR2PDE10ATLR4 | |
| SCHEMBL27144904 | 0.84 | HCRTR1 (0.38) | HTR3AHCRTR1HCRTR2PDE10ATLR4 | |
| SCHEMBL31413439 | 0.81 | HCRTR2 (0.46) | HTR3AHCRTR1HCRTR2PDE10AHRH4 | |
| SCHEMBL27152248 | 0.81 | HCRTR2 (0.46) | HTR3AHCRTR1HCRTR2PDE10AHRH4 | |
| SCHEMBL31413438 | 0.81 | HTR3A (0.40) | MTORHTR3AHCRTR1HCRTR2PIK3CA | |
| SCHEMBL27147108 | 0.81 | HTR3A (0.40) | MTORHTR3AHCRTR1HCRTR2PIK3CA | |
| SCHEMBL27139923 | 0.81 | MTOR (0.39) | MTORHTR3AHCRTR1HCRTR2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119325469-A | WEE1 degrading compounds and uses thereof | 百时美施贵宝公司 | 2025-01-17 | — | — | CN | disclosed |