Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30719046 | 0.83 | KMT2A (0.54) | RAB9AMAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL6547054 | 0.82 | NPC1 (0.45) | RAB9ANPC1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL30718956 | 0.81 | MAPT (0.46) | MAPTL3MBTL1BRD4DHODH | |
| SCHEMBL30719034 | 0.80 | MAPT (0.47) | RAB9AMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL30719032 | 0.80 | MAPT (0.47) | RAB9AMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL3811084 | 0.80 | MAPT (0.43) | RAB9AMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL16072722 | 0.79 | KCNA3 (0.46) | MAPTSMN1; SMN2L3MBTL1LMNAHTT | |
| SCHEMBL591400 | 0.79 | MAPT (0.46) | RAB9ANPC1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL635407 | 0.78 | MAPT (0.49) | RAB9ANPC1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL29560409 | 0.78 | MAPT (0.49) | RAB9ANPC1MAPTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117362141-A | Method for synthesizing axial chiral biaryl compound by palladium-catalyzed asymmetric hydrogenolysis | 中国科学院大连化学物理研究所 | 2024-01-09 | — | — | CN | disclosed |