Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795700 | 0.91 | DRD2 (0.44) | MAPTMEN1ALDH1A1RAB9AKMT2A | |
| SCHEMBL635407 | 0.90 | MAPT (0.49) | MAPTMEN1ALDH1A1RAB9AKMT2A | |
| SCHEMBL29560409 | 0.90 | MAPT (0.49) | MAPTMEN1ALDH1A1RAB9AKMT2A | |
| SCHEMBL31338576 | 0.88 | ALDH1A1 (0.39) | MAPTMEN1ALDH1A1RAB9AKMT2A | |
| SCHEMBL7795719 | 0.86 | CA12 (0.40) | MAPTMEN1ALDH1A1RAB9AKMT2A | |
| SCHEMBL23581680 | 0.85 | MAPT (0.41) | MAPTMEN1ALDH1A1RAB9AKMT2A | |
| SCHEMBL7788925 | 0.85 | MAPT (0.40) | MAPTMEN1ALDH1A1RAB9AKMT2A | |
| SCHEMBL25421451 | 0.84 | PRKDC (0.36) | MAPTMEN1ALDH1A1RAB9AKMT2A | |
| SCHEMBL30719046 | 0.84 | KMT2A (0.54) | MAPTMEN1ALDH1A1RAB9AKMT2A | |
| SCHEMBL6931868 | 0.84 | GPR84 (0.38) | MAPTMEN1ALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452537-B1 | PROCESS FOR PREPARATION OF DIPHOSPHINE COMPOUNDS AND INTERMEDIATES FOR THE PROCESS | TAKEDA PHARMACEUTICAL (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-5886182-A | REDUCING PYRIDYLPHOSPHINEOXIDE COMPOUND WITH SILANE COMPOUND IN AROMATIC SOLVENT IN PRESENCE OF AN ORGANIC BASE | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 1999-03-23 | — | — | US | disclosed |
| EP-0839819-A1 | Method of preparing optically active diphosphine ligands | Takasago International Corporation (JP) | 1998-05-06 | — | — | EP | disclosed |
| EP-0684230-A1 | 4- (R)-1'-formylethyl azetidin-2-one derivatives | Takasago International Corporation (JP) | 1995-11-29 | — | — | EP | disclosed |