Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 2/20 | 0.35 |
| ▸ | CASP6 | P55212 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30584023 | 0.74 | UGT1A1 (0.33) | — | |
| SCHEMBL30584032 | 0.74 | UGT1A1 (0.33) | PIM1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL29062471 | 0.74 | UGT1A1 (0.33) | PIM1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL748172 | 0.70 | MEN1 (0.46) | PIM1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL30584031 | 0.68 | PIM1 (0.52) | PIM1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL23900739 | 0.61 | MAPT (0.44) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL19745758 | 0.61 | MAPT (0.44) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL29542640 | 0.59 | — | — | |
| SCHEMBL33930 | 0.59 | — | — | |
| SCHEMBL913419 | 0.58 | MEN1 (0.69) | RAB9ANPC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425751-B | Polycyclic compounds as MAT2A inhibitors | 艾立康药业股份有限公司 | 2024-01-23 | — | — | CN | disclosed |