Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23496973 | 1.00 | TBXAS1 (0.56) | TBXAS1RAB9AHPGDGAAALDH1A1 | |
| SCHEMBL23496922 | 0.83 | HPGD (0.68) | HPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30719655 | 0.83 | HPGD (0.68) | HPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL23496988 | 0.81 | TBXAS1 (0.53) | TBXAS1RAB9AHPGDGAAALDH1A1 | |
| SCHEMBL7364074 | 0.76 | TBXAS1 (0.62) | TBXAS1GAAALDH1A1ALOX15MEN1 | |
| SCHEMBL24000608 | 0.75 | TBXAS1 (0.60) | TBXAS1RAB9AGAAALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL30088783 | 0.74 | TBXAS1 (0.59) | TBXAS1RAB9AGAAALDH1A1MAPT | |
| SCHEMBL13829800 | 0.73 | MAPT (0.60) | TBXAS1GAAALDH1A1MAPTALOX15 | |
| Hydrochloric Acid SCHEMBL31384254 | 0.72 | ENPP1 (0.56) | TBXAS1RAB9AGAAALDH1A1MAPT | |
| SCHEMBL29754047 | 0.72 | TBXAS1 (1.00) | TBXAS1RAB9AGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586191-A | TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof | 科罗拉多州立大学董事会法人团体 | 2024-02-23 | — | — | CN | disclosed |
| CN-117586108-A | TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof | 科罗拉多州立大学董事会法人团体 | 2024-02-23 | — | — | CN | disclosed |
| CN-111542515-B | TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof | 科罗拉多州立大学董事会法人团体 | 2023-12-05 | — | — | CN | disclosed |