SCHEMBL30719645

SCHEMBL30719645

Nc1ccc(OCCOc2cc(N)ccc2-c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCOA1 Q15788 1/20 0.53
NCOA3 Q9Y6Q9 1/20 0.53
RAB9A P51151 3/20 0.50
NPC1 O15118 1/20 0.50
CYP11B1 P15538 4/20 0.49
CYP11B2 P19099 4/20 0.49
CYP19A1 P11511 2/20 0.49
PTGDR2 Q9Y5Y4 1/20 0.46
TP53 P04637 1/20 0.45
MAPK1 P28482 1/20 0.45
MAOA P21397 2/20 0.45
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
MAOB P27338 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ALDH1A1 P00352 1/20 0.42
RECQL P46063 1/20 0.42
APP P05067 1/20 0.41
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8897316 0.85 CYP11B1 (0.56) NCOA1NCOA3RAB9ACYP11B1CYP11B2
SCHEMBL27902946 0.83 TP53 (0.54) NCOA1NCOA3RAB9ACYP11B1CYP11B2
SCHEMBL6909243 0.82 NCOA1 (0.77) NCOA1NCOA3RAB9ANPC1CYP11B1
SCHEMBL11856053 0.81 RAB9A (0.53) RAB9ANPC1CYP19A1TP53GAA
SCHEMBL3783390 0.79 MAPT (0.53) NCOA1NCOA3RAB9ANPC1CYP11B1
SCHEMBL7759094 0.78 TP53 (0.65) NCOA1NCOA3RAB9ATP53MAPK1
SCHEMBL3791209 0.78 CYP19A1 (0.74) RAB9ACYP11B1CYP11B2CYP19A1PTGDR2
SCHEMBL5583741 0.77 RAB9A (0.70) RAB9ANPC1MAOAGAAMAPT
SCHEMBL3794430 0.76 NCOA1 (0.68) NCOA1NCOA3RAB9ANPC1CYP11B1
SCHEMBL3799955 0.76 CYP19A1 (0.68) NCOA1NCOA3RAB9ACYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111777519-B Diamines 日产化学工业株式会社 2023-12-05 CN disclosed