Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.47 |
| ▸ | FEN1 | P39748 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27902946 | 0.87 | TP53 (0.54) | CYP11B1CYP11B2CYP19A1PTGDR2TP53 | |
| SCHEMBL13910996 | 0.86 | PTGDR2 (0.69) | CYP11B1CYP11B2CYP19A1PTGDR2TP53 | |
| SCHEMBL30719645 | 0.85 | NCOA1 (0.53) | CYP11B1CYP11B2CYP19A1PTGDR2TP53 | |
| SCHEMBL3783390 | 0.83 | MAPT (0.53) | CYP11B1CYP11B2CYP19A1PTGDR2TP53 | |
| SCHEMBL3791209 | 0.81 | CYP19A1 (0.74) | CYP11B1CYP11B2CYP19A1PTGDR2RAB9A | |
| SCHEMBL26153446 | 0.81 | ALDH1A1 (0.56) | PTGDR2TP53MAPK1RAB9AALDH1A1 | |
| SCHEMBL2601944 | 0.80 | GAA (0.52) | PTGDR2TP53MAPK1ALOX5APFEN1 | |
| SCHEMBL21540608 | 0.79 | ALDH1A1 (0.46) | CYP11B1CYP11B2TP53MAPK1RAB9A | |
| SCHEMBL27920645 | 0.79 | ALDH1A1 (0.61) | CYP11B1CYP11B2CYP19A1PTGDR2TP53 | |
| SCHEMBL8897321 | 0.79 | TP53 (0.56) | TP53MAPK1RAB9AALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671928-A4 | SYNTHESIS OF N-SUBSTITUTED OLIGOMERS. | CHIRON CORP (US) | 1997-04-23 | — | — | EP | disclosed |
| EP-0671928-A1 | SYNTHESIS OF N-SUBSTITUTED OLIGOMERS | CHIRON CORPORATION (US) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994006451-A1 | SYNTHESIS OF N-SUBSTITUTED OLIGOMERS | CHIRON CORPORATION (US) | 1994-03-31 | — | — | WO | disclosed |