SCHEMBL30719746

SCHEMBL30719746

Cc1oc2cnc(OCc3ccccc3F)cc2c1C(=O)NC1CCN(CCO)C1=O

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 11/20 0.39
SLC26A4 O43511 1/20 0.33
GLP1R P43220 1/20 0.33
MCHR1 Q99705 1/20 0.33
MET P08581 1/20 0.33
AXL P30530 1/20 0.33
MERTK Q12866 1/20 0.33
TRPC6 Q9Y210 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30719759 0.88 ALDH1A1 (0.36) RIPK1MET
SCHEMBL24471024 0.88 SLC26A4 (0.47) RIPK1SLC26A4MET
SCHEMBL29713018 0.88 SLC26A4 (0.47) RIPK1SLC26A4MET
SCHEMBL24470750 0.78 SLC26A4 (0.50) RIPK1SLC26A4
SCHEMBL29630081 0.78 SLC26A4 (0.45) SLC26A4
SCHEMBL24484946 0.78 SLC26A4 (0.45) SLC26A4
SCHEMBL24485720 0.78 SLC26A4 (0.44) SLC26A4
SCHEMBL29629810 0.78 SLC26A4 (0.44) SLC26A4
SCHEMBL24485012 0.77 SLC26A4 (0.42) SLC26A4
SCHEMBL24484837 0.77 SLC26A4 (0.42) SLC26A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532011-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
CN-119421883-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN claimed
WO-2023227698-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532011-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
CN-119421883-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN disclosed
WO-2023227698-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed