Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TDP2 | O95551 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26699043 | 1.00 | PTGS2 (0.50) | PTGS2MAPTLMNAALDH1A1HIF1A | |
| SCHEMBL30719907 | 1.00 | PTGS2 (0.50) | PTGS2MAPTLMNAALDH1A1HIF1A | |
| SCHEMBL30719905 | 0.90 | SLC26A4 (0.48) | PTGS2LMNATDP1TDP2L3MBTL1 | |
| SCHEMBL26699024 | 0.90 | SLC26A4 (0.48) | PTGS2LMNATDP1TDP2L3MBTL1 | |
| SCHEMBL29095725 | 0.86 | PTGS2 (0.61) | PTGS2MAPTLMNAALDH1A1HIF1A | |
| SCHEMBL29630215 | 0.86 | PTGS2 (0.61) | PTGS2MAPTLMNAALDH1A1HIF1A | |
| SCHEMBL24485054 | 0.85 | PTGS2 (0.48) | PTGS2MAPTLMNAALDH1A1HIF1A | |
| SCHEMBL24484498 | 0.84 | PTGS2 (0.47) | PTGS2MAPTLMNAALDH1A1HIF1A | |
| SCHEMBL29630207 | 0.84 | PTGS2 (0.47) | PTGS2MAPTLMNAALDH1A1HIF1A | |
| SCHEMBL30719895 | 0.84 | PTGS2 (0.52) | PTGS2MAPTLMNAALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532011-A1 | NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | Katholieke Universiteit Leuven KU Leuven Research & Development (BE) | 2025-04-09 | — | — | EP | disclosed |
| WO-2023227698-A1 | NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |