Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dezocine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 13/20 | 1.00 |
| ▸ | OPRK1 known ✓ | P41145 | 6/20 | 0.63 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.63 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dezocine SCHEMBL29811203 | 1.00 | OPRM1 (1.00) | OPRM1OPRD1OPRK1HSD11B1SIGMAR1 | |
| Dezocine SCHEMBL29682715 | 1.00 | OPRM1 (1.00) | OPRM1OPRD1OPRK1HSD11B1SIGMAR1 | |
| Dezocine SCHEMBL12720257 | 1.00 | OPRM1 (1.00) | OPRM1OPRD1OPRK1HSD11B1SIGMAR1 | |
| Dezocine SCHEMBL9685743 | 1.00 | OPRM1 (1.00) | OPRM1OPRD1OPRK1HSD11B1SIGMAR1 | |
| Dezocine SCHEMBL11874182 | 1.00 | OPRM1 (1.00) | OPRM1OPRD1OPRK1HSD11B1SIGMAR1 | |
| Dezocine SCHEMBL7781933 | 1.00 | OPRM1 (1.00) | OPRM1OPRD1OPRK1HSD11B1SIGMAR1 | |
| Dezocine SCHEMBL11874190 | 1.00 | OPRM1 (1.00) | OPRM1OPRD1OPRK1HSD11B1SIGMAR1 | |
| Dezocine SCHEMBL1369581 | 1.00 | OPRM1 (1.00) | OPRM1OPRD1OPRK1HSD11B1SIGMAR1 | |
| Dezocine SCHEMBL21081189 | 1.00 | OPRM1 (1.00) | OPRM1OPRD1OPRK1HSD11B1SIGMAR1 | |
| Dezocine SCHEMBL25583319 | 1.00 | OPRM1 (1.00) | OPRM1OPRD1OPRK1HSD11B1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 13383 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122087518-A | Method for classifying anesthetic drugs by using neural network | — | 2026-05-26 | — | — | CN | claimed |
| EP-4724049-A1 | MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF | Catalent Ontario Limited (CA) | 2026-04-15 | — | — | EP | claimed |
| EP-4100010-B1 | NITROXIDE COMPOUNDS FOR USE IN THE TREATMENT OF OPIOID-INDUCED RESPIRATORY DEPRESSION (OIRD) | UNIV CASE WESTERN RESERVE (US) | 2026-01-07 | — | — | EP | claimed |
| US-20250319074-A1 | TREATMENT AND MANAGEMENT OF AUGMENTATION IN RESTLESS LEGS SYNDROME | UNIV EAST CAROLINA (US) | 2025-10-16 | — | — | US | claimed |
| US-12440489-B2 | Organic compounds | INTRA-CELLULAR THERAPIES, INC. (US) | 2025-10-14 | — | — | US | claimed |
| US-20250255781-A1 | PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-08-14 | — | — | US | claimed |
| US-12383743-B2 | Treatment of addiction and dependency | TACA JR ARTURO C (US) | 2025-08-12 | — | — | US | claimed |
| US-20250228771-A1 | ALKALINE INTRAORAL PRODUCTS | EMPLICURE AB (publ) (SE) | 2025-07-17 | — | — | US | claimed |
| EP-4581017-A1 | NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS | Biodol Therapeutics (FR) | 2025-07-09 | — | — | EP | claimed |
| US-20250205278-A1 | METHODS AND COMPOSITIONS FOR WOUND HEALING | ABBOTT NICHOLAS L (US) | 2025-06-26 | — | — | US | claimed |
| EP-0731694-A4 | — | — | 1996-10-02 | — | — | EP | claimed |
| EP-0731694-A1 | OPIOID FORMULATIONS FOR TREATING PAIN | Euroceltique S.A. (LU) | 1996-09-18 | — | — | EP | claimed |
| CN-1130352-A | Method for relieving pain by orally administering 24-hour sustained-release opioid dosage form capable of rapidly increasing initial blood concentration of patient | EURO CELTIQUE SA (LU) | 1996-09-04 | — | — | CN | claimed |
| WO-1996014058-A1 | MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS | EURO-CELTIQUE, S.A. (LU) | 1996-05-17 | — | — | WO | claimed |
| EP-0687175-A1 | METHOD FOR TREATING EMOTIONAL OR MENTAL ILLNESS AND EMOTIONAL OR MENTAL ILLNESS CONCOMITANT WITH SEIZURES | NAGLE, John S. (US) | 1995-12-20 | — | — | EP | claimed |
| WO-1995014460-A1 | OPIOID FORMULATIONS FOR TREATING PAIN | EURO-CELTIQUE S.A. (LU) | 1995-06-01 | — | — | WO | claimed |
| EP-0647448-A1 | Orally administrable opioid formulations having extended duration of effect | Euroceltique S.A. (LU) | 1995-04-12 | — | — | EP | claimed |
| WO-1994020100-A1 | METHOD FOR TREATING EMOTIONAL OR MENTAL ILLNESS AND EMOTIONAL OR MENTAL ILLNESS CONCOMITANT WITH SEIZURES | NAGLE, JOHN, S. (US) | 1994-09-15 | — | — | WO | claimed |
| WO-1990000390-A1 | NEW SYNERGISTIC PREPARATIONS CONTAINING DEZOCINE AND A LOCAL ANAESTHETIC AND A NEW METHOD OF ALLEVIATION OF PAIN | AKTIEBOLAGET ASTRA (SE) | 1990-01-25 | — | — | WO | claimed |
| EP-0165696-A2 | Improved transdermal dosage form | AMERICAN HOME PRODUCTS CORPORATION (US) | 1985-12-27 | — | — | EP | claimed |