Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29153656 | 1.00 | AGBL2 (0.46) | AGBL2L3MBTL1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL30104818 | 0.84 | L3MBTL1 (0.48) | L3MBTL1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL29153676 | 0.84 | L3MBTL1 (0.48) | L3MBTL1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL29153634 | 0.83 | PRNP (0.42) | AGBL2L3MBTL1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL30720012 | 0.83 | PRNP (0.42) | AGBL2L3MBTL1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL8325679 | 0.80 | EGFR (0.40) | AGBL2L3MBTL1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL29153677 | 0.74 | L3MBTL1 (0.44) | AGBL2L3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL30720005 | 0.74 | L3MBTL1 (0.44) | AGBL2L3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4616764 | 0.73 | KMT2A (0.64) | MAPK1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL18366537 | 0.72 | MAPK1 (0.40) | AGBL2MAPK1SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396485-A | PARP7 inhibitors | 轩竹生物科技股份有限公司 | 2024-01-12 | — | — | CN | disclosed |