SCHEMBL30720101

SCHEMBL30720101

Cc1cc(C(F)(F)F)c(C#N)c(Br)n1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.54
KDM4E B2RXH2 10/20 0.52
GLA P06280 4/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C19 P33261 1/20 0.48
KMT2A Q03164 5/20 0.45
MEN1 O00255 4/20 0.45
BRCA1 P38398 1/20 0.45
ALDH1A1 P00352 9/20 0.45
HPGD P15428 6/20 0.45
GAA P10253 5/20 0.45
TP53 P04637 2/20 0.45
HTT P42858 2/20 0.43
LMNA P02545 1/20 0.43
PKM P14618 1/20 0.43
TSHR P16473 1/20 0.43
TDP1 Q9NUW8 4/20 0.40
POLB P06746 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9017992 0.82 KDM4E (0.40) L3MBTL1KDM4EGLACYP1A2CYP2C19
SCHEMBL1694970 0.79 L3MBTL1 (0.54) L3MBTL1KDM4EGLACYP1A2CYP2C19
SCHEMBL30978261 0.79 L3MBTL1 (0.54) L3MBTL1KDM4EGLACYP1A2CYP2C19
SCHEMBL14967240 0.79 L3MBTL1 (0.54) L3MBTL1KDM4EGLACYP1A2CYP2C19
SCHEMBL29659097 0.79 L3MBTL1 (0.54) L3MBTL1KDM4EGLACYP1A2CYP2C19
SCHEMBL29659072 0.79 L3MBTL1 (0.54) L3MBTL1KDM4EGLACYP1A2CYP2C19
SCHEMBL19212167 0.79 L3MBTL1 (0.54) L3MBTL1KDM4EGLACYP1A2CYP2C19
SCHEMBL14967275 0.77 KDM4E (0.59) L3MBTL1KDM4EGLACYP1A2CYP2C19
SCHEMBL4327152 0.76 KDM4E (0.60) L3MBTL1KDM4ECYP1A2CYP2C19KMT2A
SCHEMBL25333093 0.76 L3MBTL1 (0.50) L3MBTL1KDM4EGLACYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4688775-A1 SUBSTITUTED SULTAM COMPOUND DERIVATIVES AND THEIR PHARMACEUTICAL USE Avelos Therapeutics Inc. (KR) 2026-02-11 EP disclosed
CN-119255992-A Heterocyclic derivatives, compositions and uses thereof 北京丹擎医药科技有限公司 2025-01-03 CN disclosed
WO-2024205311-A1 SUBSTITUTED SULTAM COMPOUND DERIVATIVES AND THEIR PHARMACEUTICAL USE AVELOS THERAPEUTICS INC. (KR) 2024-10-03 WO disclosed
WO-2023226964-A1 HETEROCYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF DANATLAS PHARMACEUTICALS CO., LTD. (CN) 2023-11-30 WO disclosed