Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KHK | P50053 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3825621 | 0.83 | RECQL (0.46) | KDM4EMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL13979608 | 0.80 | KDM4E (0.43) | KDM4EMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL3832490 | 0.80 | KDM4E (0.43) | KDM4EMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL4066614 | 0.78 | KDM4E (0.64) | KDM4EMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL30720101 | 0.76 | L3MBTL1 (0.54) | KDM4EMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL317616 | 0.75 | KDM4E (1.00) | KDM4EMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL2673578 | 0.75 | KDM4E (0.60) | KDM4EMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL10288069 | 0.75 | KDM4E (0.60) | KDM4EMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL318407 | 0.75 | KDM4E (0.60) | KDM4EMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL3985050 | 0.75 | KDM4E (0.60) | KDM4EMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009144253-A1 | COMPOUNDS COMPRISING A 3-PYRIDINOL OR 5-PYRIMIDINOL RING HAVING AN ORGANOSELENO OR ORGANOTELLURO SUBSTITUENT FOR USE AS ANTIOXIDANTS | KAROLINSKA INSTITUTET INNOVATIONS AB (SE) | 2009-12-03 | — | — | WO | disclosed |
| WO-2009144253-A1 | COMPOUNDS COMPRISING A 3-PYRIDINOL OR 5-PYRIMIDINOL RING HAVING AN ORGANOSELENO OR ORGANOTELLURO SUBSTITUENT FOR USE AS ANTIOXIDANTS | KAROLINSKA INSTITUTET INNOVATIONS AB (SE) | 2009-12-03 | — | — | WO | disclosed |