Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 16/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 15/20 | 0.38 |
| ▸ | HTR2A | P28223 | 12/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30659847 | 0.82 | PARP1 (0.49) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL30459786 | 0.82 | PARP1 (0.43) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL30496984 | 0.82 | PARP1 (0.45) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL30351685 | 0.82 | PARP1 (0.40) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL30351684 | 0.81 | PARP1 (0.40) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL30936963 | 0.81 | PARP1 (0.45) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL30352049 | 0.79 | PARP1 (0.38) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL30352160 | 0.79 | PARP1 (0.38) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL30351634 | 0.78 | PARP1 (0.39) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL30212434 | 0.75 | PARP1 (0.49) | PARP1HTR2BHTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321046-A | Indazole-based compounds and related methods of use | 阿维纳斯企业公司 | 2023-12-29 | — | — | CN | disclosed |