Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 4/20 | 0.52 |
| ▸ | IKZF1 | Q13422 | 4/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 12/20 | 0.49 |
| ▸ | IKZF3 | Q9UKT9 | 7/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.46 |
| ▸ | TNF | P01375 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | IL1B | P01584 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30720911 | 0.87 | IKZF2 (0.49) | IKZF2IKZF1CRBNIKZF3DDB1 | |
| SCHEMBL22345825 | 0.85 | IKZF2 (0.61) | IKZF2IKZF1CRBNIKZF3DDB1 | |
| SCHEMBL31025903 | 0.85 | IKZF2 (0.61) | IKZF2IKZF1CRBNIKZF3DDB1 | |
| SCHEMBL25133738 | 0.82 | IKZF2 (0.51) | IKZF2IKZF1CRBNIKZF3DDB1 | |
| SCHEMBL25133737 | 0.82 | IKZF2 (0.49) | IKZF2IKZF1CRBNIKZF3DDB1 | |
| SCHEMBL30930637 | 0.81 | CRBN (0.55) | IKZF2IKZF1CRBNDDB1 | |
| SCHEMBL29767388 | 0.81 | CRBN (0.55) | IKZF2IKZF1CRBNDDB1 | |
| SCHEMBL29927258 | 0.81 | CRBN (0.51) | IKZF2IKZF1CRBNIKZF3DDB1 | |
| SCHEMBL20231931 | 0.81 | CRBN (0.51) | IKZF2IKZF1CRBNIKZF3DDB1 | |
| SCHEMBL27284747 | 0.81 | CRBN (0.55) | IKZF2IKZF1CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321046-A | Indazole-based compounds and related methods of use | 阿维纳斯企业公司 | 2023-12-29 | — | — | CN | disclosed |