Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.53 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.53 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23867200 | 1.00 | PDK1 (0.53) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL23867198 | 0.93 | PDK1 (0.52) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL4329419 | 0.89 | PDK1 (0.56) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL30524578 | 0.84 | CHRM1 (0.60) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL29849418 | 0.84 | CHRM1 (0.60) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL29928044 | 0.83 | HTR2C (0.50) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL29928240 | 0.82 | SMN1; SMN2 (0.62) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL29927422 | 0.82 | PDK1 (0.50) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL4329059 | 0.81 | PDK1 (0.71) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL25134533 | 0.81 | PDK1 (0.47) | PDK1PDK2PDK3PDK4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321046-A | Indazole-based compounds and related methods of use | 阿维纳斯企业公司 | 2023-12-29 | — | — | CN | disclosed |