Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.71 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.71 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.71 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SPR | P35270 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL952644 | 0.96 | PDK1 (0.67) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL951381 | 0.96 | PDK1 (0.67) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL2584283 | 0.96 | PDK1 (0.67) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL18711275 | 0.92 | PDK1 (0.69) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL29300886 | 0.90 | PDK1 (0.70) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL953545 | 0.90 | PDK1 (0.70) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL2380922 | 0.90 | PDK1 (0.67) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL952361 | 0.90 | PDK1 (0.70) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL8117814 | 0.90 | PDK1 (0.67) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL14018842 | 0.90 | PDK1 (0.60) | PDK1PDK2PDK3PDK4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569690-B2 | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINE CHEMICALS CO., LTD. (JP) | 2009-08-04 | — | — | US | disclosed |
| US-20060161003-A1 | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINE CHEMICALS CO., LTD. (JP) | 2006-07-20 | — | — | US | disclosed |
| EP-1548010-A1 | PROCESS FOR PRODUCING OXYCARBONYL-SUBSTITUTED PIPERAZINE DERIVATIVE | Toray Fine Chemicals Co., Ltd. (JP) | 2005-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060161003-A1 | Process for producing oxycarbonyl-substituted piperazine derivative | DHPS, AQP4, OGFOD1 | PDK1 475/4885PDK2 135/4885PDK3 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.