Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 14/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25133344 | 1.00 | TXNRD1 (0.38) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL1428159 | 0.77 | TXNRD1 (0.58) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL7836090 | 0.76 | TXNRD1 (0.56) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL7836091 | 0.76 | TXNRD1 (0.56) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL7836089 | 0.76 | TXNRD1 (0.56) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL17372594 | 0.74 | TXNRD1 (0.48) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL25133374 | 0.74 | NNMT (0.32) | — | |
| SCHEMBL29927394 | 0.74 | NNMT (0.32) | — | |
| SCHEMBL16126094 | 0.73 | TXNRD1 (0.40) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL14938577 | 0.73 | TXNRD1 (0.43) | TXNRD1S1PR4MAPTS1PR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321046-A | Indazole-based compounds and related methods of use | 阿维纳斯企业公司 | 2023-12-29 | — | — | CN | disclosed |