Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | SMO | Q99835 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116546 | 1.00 | TSHR (0.49) | TSHRMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20116221 | 0.86 | SMO (0.52) | TSHRMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30720936 | 0.86 | SMO (0.52) | TSHRMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20116127 | 0.85 | NR1H4 (0.55) | TSHRMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20660776 | 0.84 | TSHR (0.56) | TSHRMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21611300 | 0.84 | NPC1 (0.51) | TSHRMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20660824 | 0.82 | HTR1A (0.54) | TSHRMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20116547 | 0.79 | TLR9 (0.54) | TSHRMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20116374 | 0.77 | SMO (0.51) | TSHRMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20676691 | 0.77 | HTT (0.57) | TSHRMEN1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12275723-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2025-04-15 | — | — | US | disclosed |
| US-20240400546-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2024-12-05 | — | — | US | disclosed |
| US-20240300938-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2024-09-12 | — | — | US | disclosed |
| US-11970486-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-04-30 | — | — | US | disclosed |
| US-20240124435-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2024-04-18 | — | — | US | disclosed |
| US-11873298-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124435-A1 | COMPOUNDS AND USES THEREOF | NLN, ACHE, CLN6 | TSHR 4679/4885MEN1 1807/4885CYP3A4 1178/4885 |
| US-20240300938-A1 | COMPOUNDS AND USES THEREOF | NLN, ACHE, CLN6 | TSHR 4679/4885MEN1 1807/4885CYP3A4 1178/4885 |
| US-11873298-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | TSHR 4679/4885MEN1 1807/4885CYP3A4 1178/4885 |
| US-20240400546-A1 | COMPOUNDS AND USES THEREOF | NLN, ACHE, CLN6 | TSHR 4679/4885MEN1 1807/4885CYP3A4 1178/4885 |
| US-12275723-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | TSHR 4679/4885MEN1 1807/4885CYP3A4 1178/4885 |
| US-11970486-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | TSHR 4679/4885MEN1 1807/4885CYP3A4 1178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.